Difference Between Hyaloplasm and Cytosol | Hyaloplasm vs Cytosol

The key difference between hyaloplasm and cytosol is the absence and presence of cell organelles. Hyaloplasm comprises of structureless fluid while cytosol comprises of fluid and structured organelles.

Hyaloplasm and cytosol are organic fluid substances found in a cell. They can be observed in prokaryotic cells as well are eukaryotic cells. The hyaloplasm refers to the liquid portion of the cytosol, which does not comprise of any structures. In comparison, cytosol is a liquid phase which comprises of structural components of a cell apart from the nucleus.


1. Overview and Key Difference
2. What is Hyaloplasm 
3. What is Cytosol
4. Similarities Between Hyaloplasm and Cytosol
5. Side by Side Comparison – Hyaloplasm vs Cytosol in Tabular Form
6. Summary

What is Hyaloplasm?

Hyaloplasm is the fluid portion of the cytosol devoid of any structures. Therefore, hyaloplasm does not house any structures on itself. It is also called the ground substance of the cell. There are many constituents in the hyaloplasm. They are water, minerals, dissolved minerals, amino acids, sugars, and dissolved inorganic ions. Therefore, the hyaloplasm is a nutrient-rich ground substance of a cell. It is a clear fluid portion.

Hyaloplasm is important in the metabolic activities of the cell. It carries out most reactions and makes the nutrients available for cellular functions. In addition to metabolism, the hyaloplasm also aids in locomotion of the cell along with the plasma membrane.

What is Cytsol?

Cytosol is a semi-solid, nutrient-rich complex medium which provides surface area for cellular organelles and other cellular structures except for the cell nucleus. The outer boundary of the cytosol is the plasma membrane. Cytosol is rich in components such as proteins, carbohydrates, globular structures, ions, vitamins, and minerals. Moreover, similar to the hyaloplasm, the main constituent present in the cytosol is water.