Difference Between Polarised and Non Polarised Cells | Polarised vs Non Polarised Cells

The key difference between polarised and non polarised cells is that polarised cells undergo repolarisation to become polarised where the resting membrane potential is restored after each event of depolarisation while non polarised cells undergo depolarisation to become non polarised where the resting membrane potential is lost by the change in the polarisation of the cell membrane.

Repolarization makes cells polarised while depolarization makes cells non polarised. Both depolarization and repolarization are two sequential processes that take place in the cell membrane during the transmission of nerve impulses. Hence, polarised and non polarised cells occur due to the alteration of charge of the inner membrane of the cell during both processes. The inner membrane has a less negative charge during depolarization (non polarised cell). However, this is restored during repolarization (polarised cell).


1. Overview and Key Difference
2. What are Polarised Cells
3. What are Non Polarised Cells
4. Similarities Between Polarised and Non Polarised Cells
5. Side by Side Comparison – Polarised vs Non Polarised Cells in Tabular Form
6. Summary

What are Polarised Cells?

Polarised cells undergo repolarization to become polarised. Repolarization is a process where, followed by a depolarization event, restoration of the resting membrane potential takes place. During repolarization, closure of membrane sodium channels takes place. Therefore, this creates a less negative charge inside the cell. At the same time, membrane potassium channels open up since more positive ions (Na+) are present inside the cell. Hence, potassium ions (K+) move out from the cell through the potassium channels, making the cell interior more negative. Therefore, a combination of all these events restores the resting membrane potential and convert the cell into a polarised stage.